Frank Henenlotter's BASKET CASE 2 picks up right where the original BASKET CASE leaves off. After surviving the fall from their hotel room window, Duane Bradley and his misshapen, basket-dwelling brother Belial are taken to the city hospital. By now, their attempt at leading a secret life is blown, and the pair have become media darlings across the country. Meanwhile, Duane's long-lost Aunt learns of their situation and, along with her pregnant daughter Susan, helps them escape from the confines of the hospital and the eye of the press. Duane and Belial's aunt, known as Granny Ruth, takes them under her wing at her mansion, which serves as a safe haven for hideously deformed freaks of all shapes and sizes. Unfortunately, the whereabouts of this dynamic duo don't remain secret for too long, and Duane and Belial team up with Susan, Granny Ruth, and her houseful of mutants to devise a plan to do away with the exploitative reporters once and for all.

A faulty blood transfusion turns Dracula's wife black.

Michael Sopkiw hitches a ride to Brazil to dig up some dinosaur bones. Once in Brazil he gets in a few tangles with the locals and manages to secure a ride on a charter flight deep into Amazonia. All hell breaks loose as the plane crashes deep in the heart of the jungle, leaving Sopkiw, megalomaniac Soares, and a bunch of super models on their own to trek back to society. The group runs into cannibals, quick sand, murderous animals, and a renegade mine run by slave owners.

Following the events of Alien vs. Predator, and the maturation of the chestburster that erupted from the body of Scar (the Predator that defeated the Alien Queen) into an adult Predalien, the Predator scout ship crashes in the woods of Gunnison County. A local, Buddy Benson, and his son, Sam, are hunting in the forest and witness the crash, but they are chased and are implanted with alien embryos by facehuggers along with several homeless people living in the sewers. Meanwhile another Predator lands seeking out the Alien and destroying evidence of their presence on Earth. The dwellers of the town find themselves in the middle of a battlefield between the two deadly extraterrestrial creatures, and the small group of survivors splits between the leadership of Sheriff Eddie Morales and the bad-boy Dallas Howard. Both have different opinions about the best means to escape from the beings.